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Aparna Kalyan Selected Research

aprutumab ixadotin

10/2019First-in-Human Phase I Study of Aprutumab Ixadotin, a Fibroblast Growth Factor Receptor 2 Antibody-Drug Conjugate (BAY 1187982) in Patients with Advanced Cancer.

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Aparna Kalyan Research Topics

Disease

20Neoplasms (Cancer)
08/2022 - 02/2014
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2020 - 01/2016
4Colorectal Neoplasms (Colorectal Cancer)
02/2018 - 12/2015
3Adenocarcinoma
01/2020 - 06/2017
2Stomach Neoplasms (Stomach Cancer)
10/2019 - 12/2018
2Biliary Tract Neoplasms (Biliary Tract Cancer)
01/2019 - 01/2016
2Hepatocellular Carcinoma (Hepatoma)
12/2015 - 05/2015
1Cholangiocarcinoma
08/2022
1Hepatitis B
02/2021
1Radiation Pneumonitis
01/2020
1Anemia
10/2019
1Proteinuria
10/2019
1Triple Negative Breast Neoplasms
10/2019
1Thrombocytopenia (Thrombopenia)
10/2019
1Body Weight (Weight, Body)
10/2019
1Carcinogenesis
12/2018
1Dysbiosis
12/2018
1Pneumonia (Pneumonitis)
01/2018
1Infections
01/2018
1Microsatellite Instability
08/2017
1Circulating Neoplastic Cells
10/2016
1Rectal Neoplasms (Rectal Cancer)
08/2016
1Endometrial Neoplasms (Endometrial Cancer)
06/2016
1Genomic Instability
04/2016
1Aneuploidy (Aneuploid)
01/2016
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2015
1Breast Neoplasms (Breast Cancer)
12/2015
1Brain Stem Neoplasms (Brain Stem Tumor)
12/2015
1Multiple Myeloma
12/2015
1Adenoid Cystic Carcinoma (Cylindroma)
11/2015
1Lung Neoplasms (Lung Cancer)
02/2014
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
02/2014
1Melanoma (Melanoma, Malignant)
02/2014
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2014

Drug/Important Bio-Agent (IBA)

3Biomarkers (Surrogate Marker)IBA
01/2022 - 04/2016
3Pharmaceutical PreparationsIBA
10/2019 - 12/2015
3Immune Checkpoint InhibitorsIBA
12/2018 - 02/2014
2GemcitabineFDA Link
01/2020 - 06/2017
2Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
10/2019 - 01/2016
2130-nm albumin-bound paclitaxelIBA
01/2019 - 06/2017
2pembrolizumabIBA
12/2018 - 02/2018
2Proteins (Proteins, Gene)FDA Link
01/2016 - 11/2015
1Yttrium-90IBA
08/2022
1Serum AlbuminIBA
08/2022
1Circulating Tumor DNAIBA
01/2022
1Hepatitis B Vaccines (Hepatitis B Vaccine)IBA
02/2021
1IpilimumabIBA
01/2020
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
10/2019
1Immunoconjugates (Immunoconjugate)IBA
10/2019
1aprutumab ixadotinIBA
10/2019
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2019
1Bevacizumab (Avastin)FDA Link
01/2019
1Fluorouracil (Carac)FDA LinkGeneric
01/2019
1Oxidoreductases (Dehydrogenase)IBA
01/2019
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2019
1Leucovorin (Folinic Acid)FDA Link
01/2019
1NivolumabIBA
01/2018
1histidine-rich proteinsIBA
10/2017
1Calcibiotic Root Canal SealerIBA
10/2017
1AntibodiesIBA
08/2017
1folfirinoxIBA
06/2017
1Cell-Free Nucleic AcidsIBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2016
1Metformin (Glucophage)FDA LinkGeneric
06/2016
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2016
1Phosphotransferases (Kinase)IBA
01/2016
1CholesterolIBA
12/2015
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2015
1Cytotoxins (Cytolysins)IBA
11/2015
1Neoplasm Antigens (Tumor Antigens)IBA
02/2014
1VaccinesIBA
02/2014
1ErbB Receptors (EGF Receptor)IBA
02/2014
1AntigensIBA
02/2014
1Glycoproteins (Glycoprotein)IBA
02/2014
1Cancer VaccinesIBA
02/2014

Therapy/Procedure

12Therapeutics
01/2019 - 02/2014
8Immunotherapy
01/2020 - 02/2014
6Drug Therapy (Chemotherapy)
08/2022 - 12/2015
1Artificial Respiration (Mechanical Ventilation)
09/2020
1Injections
01/2020
1Neoadjuvant Therapy
08/2016
1Radiotherapy
01/2016